Changes Made to HIV Infections Guidelines

The U.S. guidelines for preventing and treating HIV-associated opportunistic infections have been given a complete update for the first time in five years, the National Institutes of Health (NIH) reports.

Guidelines for Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents” was released April 10 by the NIH and the Centers for Disease Control and Prevention (CDC) in cooperation with the HIV Medicine Association of the Infectious Diseases Society of America (IDSA).

Major changes in guidelines include:

  • Emphasis of effective antiretroviral therapy in augmenting immune function;
  • Information on diagnosis and management of immune reconstitution inflammatory syndrome information;
  • Prevention and treatment of hepatitis B and C infections information;
  • Information on interferon-gamma release assays for the detection of latent mycobacterium tuberculosis infection;
  • Updated information on interactions between antiretroviral drugs and drugs used to treat opportunistic infections; and
  • A new section on malaria and other tropical diseases that may become opportunistic infections in HIV-infected immigrants to the United States and in HIV-infected American travelers.

A final draft of the corresponding pediatric version of these guidelines is expected to be published later this year, according to a NIH press release issued April 16.

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