It's my understanding, that modifier 53, is used for those procedures generally done under anesthesia. In my modifier book "Coding with Modifiers" second edition, it gives the definition as:
"In certain circumstances, the PHYSICIAN may elect to terminate a surgical or diagnositic procedure. Due to extenuating circumstances or those that threaten the well being of the patient, it may be necessary to indicate that a surgical or diagnostic procedure was started but discontinued. This circumstance may be reported by adding the modifier 53 to the code reported by the physician for the discontinued procedure. Note: This modifier is not used to report the elective cancellation of a procedure prior to the patient's anesthesia induction and/or surgical preparation in the operating suite."
I don't think I would use the 53 modifier in the instance of a nurse giving an injection.
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