Pathology/Lab Coding Alert

Reader Questions:

Payer Leads Pap Interpretation Code Choice

Question: What’s the difference between G0141 and 88141, and when should we use one code over the other?

Texas Subscriber

Answer: Both codes describe physician interpretation of an abnormal Pap smear:

  • G0141 (Screening cytopathology smears, cervical or vaginal, performed by automated system, with manual rescreening, requiring interpretation by physician)
  • 88141 (Cytopathology, cervical or vaginal (any reporting system), requiring interpretation by physician)

The difference between the codes is that G0141 describes interpretation following a screening Pap test, while 88141 describes interpretation following a diagnostic Pap test for Medicare beneficiaries. Non-Medicare payers accept 88141 for interpretation of abnormal screening or diagnostic Pap tests.

Medicare requires you to use HCPCS Level II codes for screening Pap tests, including the physician interpretation when the findings are abnormal.

Either G0141 or 88141 is appropriate when the technical Pap test results in abnormal findings, such as the following:

  • Atypical endocervical, endometrial, or glandular cells not otherwise specified (R87.619)
  • Atypical squamous cells of undetermined significance (ASCUS, R87.610)
  • Atypical squamous cells, cannot exclude high grade squamous intraepithelial lesion (ASC-H, R87.611)
  • Low- or high-grade squamous intraepithelial lesion (LGSIL R87.612, or HGSIL R87.613)
  • Reparative/reactive cellular changes, such as due to radiation, viral infection, etc. (R87.618)
  • HPV-positive patient, high or low risk (R87.810, R87.820).