Regulatory Information Center Updates: December 16, 2025


These updates are now available on Codify by AAPC. You can access them by selecting Publications/Regulatory Information from the top menu or by clicking the links below.

CMS Center/Transmittals

Document #

Health Insurance Portability and Accountability Act (HIPAA) Electronic Data Interchange Front-End Updates for April 2026

R13442OTN

Removal of Chimeric Antigen Receptor (CAR) T-cell Therapy and Risk Evaluation Mitigation Strategy (REMS) – NCD 110.24 and the “KX’ Modifier for CAR-T Cell Therapy Claims R13432CP
The Fiscal Intermediary Shared System (FISS) Submission of Copybook Files to the Provider and Statistical Reimbursement (PS&R) System R13484FM
Instructions for Downloading the Medicare ZIP Code File for January 2026 Files R13473CP
Home Health Prospective Payment System (HH PPS) Rate Update for Calendar Year (CY) 2026 R13488CP
Provider Education for the Review Choice Demonstration (RCD) for Inpatient Rehabilitation Facility Services (IRFs) R13526OTN
NCD 20.40- Renal Denervation (RDN) for Uncontrolled Hypertension R13522NCD
NCD 20.40- Renal Denervation (RDN) for Uncontrolled Hypertension R13522CP
OIG HHS/Reports Document #

The National Institutes of Health Generally Implemented the Safe Workplace Federal Reporting Requirement, but Opportunities Exist To Improve the Reporting and Monitoring Processes

A-05-24-00002

Arkansas Could Better Ensure That Intermediate Care Facilities for Individuals With Intellectual Disabilities Comply With Federal Requirements for Life Safety, Emergency Preparedness, and Infection Control OAS-25-06-029
The Indian Health Service Did Not Ensure That Commissioned Corps Officers’ Background Investigations Complied With Federal Requirements A-01-24-01500
New Jersey Should Improve Its Oversight of Nursing Homes’ Compliance With Background Check Requirements A-02-23-01011
Federal Register Proposed Rule Document #
Medicare Program; Alternative Payment Model Updates and the Increasing Organ Transplant Access (IOTA) Model 2025-22543
Federal Register/Notice Document #
Agency Information Collection Activities: Proposed Collection; Comment Request 2025-22426
Agency Information Collection Activities: Proposed Collection; Comment Request 2025-22478
Agency Information Collection Activities: Submission for OMB Review; Comment Request 2025-22482
Agency Information Collection Activities: Submission for OMB Review; Comment Request 2025-22974
Agency Information Collection Activities: Proposed Collection; Comment Request 2025-22975