General Coding:
Inject These New Codes Into Your Coding Arsenal
Published on Thu May 22, 2025
Question: Are there any new HCPCS injection codes I should be aware of? I feel like an update should have posted by now, but I haven’t seen anything.
Alaska Subscriber
Answer: Yes, there are quite a few new injection codes about to go live on July 1, 2025. Now is the perfect time to familiarize yourself with them.

Here's a list of the new HCPCS injection codes you should review before July 1:
- J0165 (Injection, epinephrine, not otherwise specified, 0.1 mg)
- J0166 (Injection, epinephrine (bpi), not therapeutically equivalent to j0165, 0.1 mg)
- J0167 (Injection, epinephrine (hospira), not therapeutically equivalent to j0165, 0.1 mg)
- J0168 (Injection, epinephrine (international medication systems), not therapeutically equivalent to j0165, 0.1 mg)
- J0169 (Injection, epinephrine (adrenalin), not therapeutically equivalent to j0165, 0.1 mg)
- J0616 (Injection, metoprolol tartrate, 1 mg)
- J0618 (Injection, calcium chloride, 2 mg)
- J1163 (Injection, diltiazem hydrochloride, 0.5 mg)
- J2312 (Injection, naloxone hydrochloride, not otherwise specified, 0.01 mg)
- J2313 (Injection, naloxone hydrochloride (zimhi), 0.01 mg)
- J3373 (Injection, vancomycin hydrochloride, 10 mg)
- J3374 (Injection, vancomycin hydrochloride (mylan) not therapeutically equivalent to j3373, 10 mg)
- J3375 (Injection, vancomycin hydrochloride (xellia), not therapeutically equivalent to j3373, 10 mg)
- J7356 (Injection, foscarbidopa 0.25 mg/foslevodopa 5 mg)
- J9275 (Injection, cosibelimab-ipdl, 2 mg)
- J9341 (Injection, thiotepa (tepylute), 1 mg)
- Q5153 (Injection, aflibercept-yszy (opuviz), biosimilar, 1 mg).
Lindsey Bush, BA, MA, CPC, Production Editor, AAPC