WIthout seeing the op note, it sounds like you'd code both techniques separately, such as 45385 and 45380 - 59 (or -XS for MCR), if a snare was used on one polyp and a cold biopsy forceps on the other.
The answer of the "33 or PT on both" is a weird one, based on payers payment behaviors. I include the -33 or -PT on both because I haven't seen any documentation stating we should NOT do that. If anyone out there has any such documentation, please share. What's weird is that I get denials back from some payers saying I can't use the -33 or the -PT on the SECOND technique. Again, if anyone has any documentation regarding this, please share. Apparently some payers are processing only the first technique as the 'screening' and not the remaining techniques. There may be 'official' explanantions out there in policies somewhere why they only allow screening mods on the first one but I haven't found any yet so I keep putting the screening mod on all, if applicable.
Hope that helps.