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This is a Proprietary Laboratory Analyses (PLA) code, meaning that the code applies to only one unique lab test made by a specific manufacturer or performed by a specific lab. Report 0681U only for Smoke Signature© (Saliva) from Quantigen®. This test uses saliva to analyze DNA methylation of two markers: one content marker, cg05575921 in the AHRR gene, and one normalizing marker, cg08141395. The test uses methylation–sensitive digital polymerase chain reaction (PCR). The results are analyzed by an algorithm and reported as quantitative percent methylation and estimated average cigarette use per day.
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