Medicare denial for 88305 and 88342

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I got denial for 88305 and 88342 from Medicare. According to remittance advice modifier(S) was missing. Do I need to apply modifier 59 to 88305? I am confused I did not know that any modifier needed for those codes.
 
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our Dermatology group owes Dermapathology lab, and modifier 26 is not applicable in this case. I was thinking about 59 or 76; but i have only one procedure for surgical pathology and one for stain.
 
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