Chandanahp
New
We need CPT code for gene fusion and point mutation for below genes.
Methodology:
Urine: RNA is extracted from a Urine sample using the KingFisher Flex, it is reverse transcribed, and then followed by preamplification. The DNA is then loaded on Qiagen’s QiaCuity digital PCR instrument that holds 8 samples on a 25K reaction well plate.
Tissue: RNA is extracted from a Paraffin Embedded Block after deparaffinization KingFIsher Flex it is reverse transcribed, and then followed by preamplification, The DNA is then loaded on Qiagen’s QiaCuity digital PCR instrument that holds 8 samples on a 25K reaction well plate.
Gene fusion
FGFR3 TACC3V1
FGFR3 TACC3V3
FGFR2 CASP7
FGFR3 BAIAP2L1
Point mutation FGFR3 G370C
FGFR3 R248C
FGFR3 S249C
FGFR3 Y373C
Also, these 4 genes TACC3V1, TACC3V3, CASP7 and BAIAP2L1 are co-expressed either with FGFR2 or FGFR3, their dysregulation is important for Bladder cancers.
Methodology:
Urine: RNA is extracted from a Urine sample using the KingFisher Flex, it is reverse transcribed, and then followed by preamplification. The DNA is then loaded on Qiagen’s QiaCuity digital PCR instrument that holds 8 samples on a 25K reaction well plate.
Tissue: RNA is extracted from a Paraffin Embedded Block after deparaffinization KingFIsher Flex it is reverse transcribed, and then followed by preamplification, The DNA is then loaded on Qiagen’s QiaCuity digital PCR instrument that holds 8 samples on a 25K reaction well plate.
Gene fusion
FGFR3 TACC3V1
FGFR3 TACC3V3
FGFR2 CASP7
FGFR3 BAIAP2L1
Point mutation FGFR3 G370C
FGFR3 R248C
FGFR3 S249C
FGFR3 Y373C
Also, these 4 genes TACC3V1, TACC3V3, CASP7 and BAIAP2L1 are co-expressed either with FGFR2 or FGFR3, their dysregulation is important for Bladder cancers.